Sphingolipids and a process thereto

Details Sphingolipids and a process thereto Sphingolipids and a process thereto

1997-03-24

1999-09-28

Wortman, Donna C.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Lipid or oil

A61K 4500

Patent

active

059584262

ABSTRACT:
A process for novel sphingolipids and other secondary sphingosine-based compounds is provided which comprises the culturing of an appropriate fungus, harvesting mycelium from the fungus and isolating the sphingolipid from the mycelium. The sphingosine-based materials inhibit protein kinase C, provide an anti-inflammatory effect or provide an anti-tumor effect; furthermore, these sphingosine-based materials provide protection for plants against pathogenic microorganisms.

REFERENCES:
patent: 4937232 (1990-06-01), Bell et al.
Pivot et al., "Isolation, Characterization and Biological Activity of Inositol Sphingolipids. . .," Lipids 29(1994) pp. 21-25.
Jin et al., "Ophidiacerebrosides: Cytotoxic Glyco-Sphingolipids. . ." Jorg Chem 59:144-147 (1994).
Lhomme et al., "Structural Investigations and Biological. . ." Eur J Biochem 191:203-209 (1990).
Itasaka et al., "Analysis of Phospho-and Phosphono-Sphingolipids. . ." J Biochem 95:1671-75, (1984).
Kaneshiro et al., "Characterizations of six ethanolamine. . .," J Lipid Res 25:369-377 (1984).
Stein et al., "Ceramid-1-Phosphoethanolamine. . .," Z. Naturforsch 43b:1063-1067 (1988).

Affiliated with

Also associated with

Rating

Sphingolipids and a process thereto does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sphingolipids and a process thereto, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sphingolipids and a process thereto will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-700238