Spheroidal silica

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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424 78, 424 79, 424 81, 424408, 424409, 424499, 424501, 426650, 42840224, 512 4, A61K 908, A61K 950, A61K 746, B32B 516

Patent

active

050116908

ABSTRACT:
Porous spheroidal silica having a particle size in the range 1 to 400 microns, axial ratios of 1:1 to 1:12 has up to 50% by weight of the SiO.sub.2 of included material, such as for example perfumes, flavoring materials, pigments, germicides, bactericides, fungicides, bleaching agents, skin benefit agents, therapeutic agents, dispersed in the silica as particles or droplets in the size range 0.01 to 10 .mu.m. The spheroids can be made by mixing together an aqueous, stabilized silica sol containing dispersed therein up to 50% by weight of the silica of an included material and an aqueous solution of a non-adsorbing polymer to form a phase separated system comprising silica droplets containing included material in a polymer-rich continuous phase and condensing the silica sol to aggregate the droplets to form silica spheroids containing the dispersed included material. The included material can be released in use by e.g. wetting, attrition, dissolution, pH change, heating.

REFERENCES:
patent: 3939260 (1976-02-01), Lafon
patent: 4183911 (1980-01-01), Smithies et al.
patent: 4255286 (1981-03-01), Berek et al.
patent: 4708859 (1987-11-01), Chevallier
patent: 4752459 (1988-06-01), Pepper
patent: 4762736 (1988-08-01), Garvey et al.
patent: 4772511 (1988-09-01), Wood et al.
patent: 4778667 (1988-10-01), Garvey et al.

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