Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1978-12-11
1980-12-30
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424267, 424320, 424330, 424DIG14, A61K 3113
Patent
active
042423597
ABSTRACT:
Disclosed is a method for treating mammalian spermatozoa with amphipathic amines in order to induce loss of fertility and/or head-tail cleavage of the sperms under mild physiological conditions. In the presence of primary alkyl or cycloalkyl amines containing between 4 to 7 carbon atoms at concentrations of about 15 .lambda./ml, sperms are rapidly dissociated into heads and tails under physiological pH- and temperature-conditions. Further disclosed are topical contraceptive compositions containing amphipathic amines.
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Chemical Abstracts 70:86091h (1969)
Chemical Abstracts 70:65542t (1969)
Cooper George W.
Young Ronald J.
Cornell Research Foundation Inc.
Schenkman Leonard
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