Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2007-06-12
2007-06-12
Chism, B. Dell (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C514S002600, C514S012200
Reexamination Certificate
active
10809654
ABSTRACT:
The present invention relates to sperm specific surface proteins, nucleic acid sequences encoding those proteins and antibodies raised against those proteins. Compositions comprising the sperm specific proteins or inhibitors of said proteins can be used in contraceptive applications.
REFERENCES:
patent: 5602005 (1997-02-01), Herr et al.
patent: 5830472 (1998-11-01), Herr et al.
patent: 2002/0102604 (2002-08-01), Edwards et al.
patent: WO 98/00486 (1998-01-01), None
patent: WO 99/11293 (1999-03-01), None
patent: WO 01/12708 (2000-03-01), None
patent: WO 01/42451 (2000-12-01), None
O'Hern et al., Biology of Reproduction, 1995, vol. 52, pp. 331-339.
Naz, Rajesh K: “Application of Sperm Antigens in Immunocontraception”, Frontiers in Bioscience 1, e87-95, Sep. 1, 1996.
O'Hern, Patricia A. et al: “Reversible Contraception in Female Baboons Immunized with a Synthetic Epitope of Sperm-Specific Lactate Dehydrogenase”, Biology of Reproduction, vol. 52, pp. 331-339, (1995).
DATABASE EMBL ′Online!, Accession No. AF203447, Nov. 12, 2000, Hao, Z. et al.; “Homo sapienssperm acrosome membrane protein SAMP32, mRNA, complete cds”.
Database EMBL ′Online!, Accession No. AW173256, Nov. 17, 1999, National Cancer Institute, Cancer Genome Anatomy Project (CGAP): “Homo sapienscDNA clone”.
Database EMBL ′Online!, Accession No. AA824354, Feb. 20, 1998, National Cancer Institute, Cancer Genome Anatomy Project (CGAP): “Homo sapienscDNA clone”.
Database EMBL ′Online, Accession No. AA431165, May 25, 1997, Hillier, L. et al,: “zw71g10.r1 Soares—testis—NHTHomo sapienscDNA clone”.
Database Geneseq [Online], Accession No. AAV63171, Jan. 12, 1999, Agostino MJ, et al.: “cDNA from clone cf50—1 which encodes a secreted protein”.
Database Geneseq [Online], Accession No. AAA37094, Aug. 8, 2000, Baker, K et al,: “Human PRO1418 (UNQ732) cDNA Sequence SEQ ID No. 264”.
Database Geneseq [Online], Accession No. AAW80397, Jan. 12, 1999, Agostino MJ et al: “A Secreted Protein Encoded by Clone cf50131”.
Database Geneseq [Online], Accession No. AAY99412, Aug. 8, 2000, Baker, K et al, “Human PRO1418 (UNQ732) Amino Acid Sequence SEQ ID No. 265”.
Chen, Michellee S., et al.: “Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin a6b1: Implications for Murine Fertilization”, PNAS, vol. 96, No. 21, pp. 11830-11835, Oct. 12 1999.
Le Noir, Francois, et al.: “Severely Reduced Female Fertility in CD9-Deficient Mice”, SCIENCE, vol. 287, Jan. 14, 2000.
Diekman, Alan B. et al,: “N-linked glycan of a sperm CD52 glycoform associated with human infertility”, FASEB, vol. 13, pp. 1303-1308, Aug. 1999.
Miyado, Kenji, et al.: “Reguirement of CD9 on the Egg Plasma Membrane for Fertilization”, SCIENCE, vol. 287, Jan. 14, 2000.
Schellenberger, V., Turck, C. W., Hedstrom, L. and Ritter, W. J. (1993). Mapping the S' Subsites of Serine Proteases Using Acyl Transfer to Mictures of Peptide Mucleophiles. Biochemistry, vol. 32, pp. 4349-4353.
Hao Zhonglin
Herr John C.
Jayes Friederike L.
Shetty Jagathpala
Wolkowicz Michael J.
Chism B. Dell
Sparks Rodney L.
University of Virginia Patent Foundation
LandOfFree
Sperm specific proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sperm specific proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sperm specific proteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3885948