Sperm antigen corresponding to a sperm zone binding protein auto

Details Sperm antigen corresponding to a sperm zone binding protein auto Sperm antigen corresponding to a sperm zone binding protein auto

1995-06-06

1998-09-29

Scheiner, Laurie A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 721, 435 79, 435 792, 4352523, 435 711, 436506, 436518, 436536, 436811, 436906, 4241391, 4241851, G01N 3353, G01N 33536, G01N 33535, G01N 33564

Patent

active

058144560

ABSTRACT:
The present invention involves DNA encoding a mammalian Sp 17 protein, particularly human Sp17 protein, or antigenic peptides which are fragments thereof, along with said antigenic fragments. These proteins and peptides are useful as immunocontraceptive agents and/or for the diagnosis of autoimmune infertility. Avirulent host cells which express the antigenic proteins or peptides and which are useful as immunocontraceptive agents are also disclosed.

REFERENCES:
patent: 5175148 (1992-12-01), O'Rand et al.
R.T. Richardson, et al; Cloning and Sequencing of the Rabbit Sperm Zona Binding Protein, RSA-3; Presence of a Sulfate Binding Region, Mol. Biol. Cell 3 No. 15a (1992).
R.B. Shabanowitz et al; Molecular Changes in the Human Zona Pellucida Associated with Fertilization and Human Sperm-Zona Interactions, Ann. N.Y. Acad. Sci. 541, pp. 621-632 (1988).

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