Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1993-12-10
1996-01-02
Mosher, Mary E.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435 691, 4351723, 4353201, 4352402, 4352542, 43525421, 536 231, 536 235, 536 253, 424 932, 4242001, C12N 121, C12N 1512, C12N 119, C12N 510
Patent
active
054807999
ABSTRACT:
The present invention involves DNA encoding a mammalian Sp 17 protein, particularly human Sp17 protein, or antigenic peptides which are fragments thereof, along with said antigenic fragments. These proteins and peptides are useful as immunocontraceptive agents and/or for the diagnosis of autoimmune infertility. Avirulent host cells which express the antigeenic proteins or peptides and which are useful as immunocontraceptive agents are also disclosed.
REFERENCES:
patent: 5175148 (1992-12-01), O'Rand et al.
R. T. Richardson and M. G. O'Rand; Cloning and Sequencing of the Rabbit Sperm Zona Binding Protein, RSA-3; Mol. Biol. Cell 3, 15a (1992).
R. B. Shabanowitz and M. G. O'Rand; Molecular Changes in the Human Zona Pellucida Associated with Fertilization and Human Sperm-Zona Interactions; Ann. N.Y. Acad. Sci. 541, pp. 621-632 (1988).
Lea Isabel A.
O'Rand Michael G.
Richardson Richard T.
Widgren Esther E.
Mosher Mary E.
Scheiner Laurie
The University of North Carolina at Chapel Hill
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