Spectrometric characterization of pharmaceutical heterogeneity

Details Spectrometric characterization of pharmaceutical heterogeneity Spectrometric characterization of pharmaceutical heterogeneity

2011-01-04

2011-01-04

Lauchman, L. G (Department: 2877)

Optics: measuring and testing

By dispersed light spectroscopy

Utilizing a spectrometer

C356S300000, C356S072000

Reexamination Certificate

active

07864316

ABSTRACT:
In one general aspect, a spectroscopic method for monitoring heterogeneity of a sample is disclosed. In this method, sampled spectroscopic measurements are acquired over a range of different micro locations in a macro-sample of the sample. This step is repeated for micro-locations in further macro-samples of the sample, and a statistical measure of chemical heterogeneity is derived from the acquisitions. In another general aspect, differently sized samples are acquired, and a statistical measure of chemical heterogeneity is derived from these acquisitions.

REFERENCES:
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patent: 6517230 (2003-02-01), Afnan et al.
patent: 7075645 (2006-07-01), Gehrlein et al.
patent: 2004/0019462 (2004-01-01), Gehrlein et al.
patent: 2004/0057650 (2004-03-01), Folestad
patent: WO 02/18912 (2002-03-01), None

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