Optical: systems and elements – Compound lens system – Microscope
Patent
1997-06-18
1999-11-09
Horlick, Kenneth R.
Optical: systems and elements
Compound lens system
Microscope
359391, 359396, 536 231, 536 243, 435 6, 422 50, G02B 2106, C07H 2104, G01N 2100, C12Q 168
Patent
active
059825340
ABSTRACT:
An illumination apparatus with a specimen slide holder, an illumination source, an optical cavity producing multiple reflection of illumination light to a specimen comprising a first and a second reflective surface arranged to achieve multiple reflections of light to a specimen is provided. The apparatus can further include additional reflective surfaces to achieve the optical cavity, a slide for mounting the specimen, a coverslip which is a reflective component of the optical cavity, one or more prisms for directing light within the optical cavity, antifading solutions for improving the viewing properties of the specimen, an array of materials for analysis, fluorescent components, curved reflective surfaces as components of the optical cavity, specimen detection apparatus, optical detection equipment, computers for analysis of optical images, a plane polarizer, fiberoptics, light transmission apertures, microscopic components, lenses for viewing the specimen, and upper and lower mirrors above and below the specimen slide as components of the optical cavity. Methods of using the apparatus are also provided.
REFERENCES:
patent: 2039219 (1936-03-01), Hausser et al.
patent: 3432275 (1969-03-01), Unger
patent: 3705000 (1972-12-01), Guerra
patent: 3879106 (1975-04-01), McCormick
patent: 4896966 (1990-01-01), Boisseau et al.
patent: 4906083 (1990-03-01), Sattler
patent: 5033834 (1991-07-01), Corder et al.
patent: 5315375 (1994-05-01), Allen
patent: 5326398 (1994-07-01), Kelley et al.
patent: 5417576 (1995-05-01), Hill
patent: 5545561 (1996-08-01), Lleonart Alibertas
patent: 5665599 (1997-09-01), Minuth
Killioniemi et al., Science 258:818-820 (1992).
Fodor et al., Science 251:767-773 (1991).
Sheldon et al., Clinical Chemistry 39(4):718-719 (1993).
Kozal et al., Nature Medicine 2(7):753-759 (1996).
Wittrup, et al., Fluorescence Array Detector for Large-Field Quantitative Fluorescence Cytometry, Cytometry 16:206-213 (1994).
Albertson Donna
Pinkel Daniel
Sudar Damir
Horlick Kenneth R.
Siew Jeffrey
The Regents of the University of California
LandOfFree
Specimen illumination apparatus with optical cavity for dark fie does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Specimen illumination apparatus with optical cavity for dark fie, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Specimen illumination apparatus with optical cavity for dark fie will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1464241