Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 4 to 5 amino acid residues in defined sequence
Reexamination Certificate
2008-10-28
2010-10-19
Nickol, Gary B. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
4 to 5 amino acid residues in defined sequence
C530S324000, C530S326000, C530S328000
Reexamination Certificate
active
07816490
ABSTRACT:
Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
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Aramburu Jose
Hogan Patrick G.
Rao Anjana
Fish & Richardson P.C.
Immune Disease Institute, Inc.
Nickol Gary B.
Stoica Elly-Gerald
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