Specific diagnostic for feline infectious peritonitis antibodies

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 71, 435 792, 435 793, 435 794, 536 2372, C12Q 170, G01N 3350

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060338458

ABSTRACT:
The present invention is based on the discovery of an antigenic site in the unique 7B polypeptide sequence of Feline Infectious Peritonitis Virus. Specific and sensitive methods for detecting cats infected with Feline Infectious Peritonitis Virus are provided. In particular, methods for determining whether an organism is infected with Feline Infectious Peritonitis Virus comprising providing a peptide or polypeptide including at least one antigenic site from the unique 7B polypeptide therein, contacting the peptide or polypeptide with serum containing antibodies from the organism, and determining whether the antibodies in the serum bind to the peptide or polypeptide. PCR based diagnostics are also provided.

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