Specific binding assay method and reagent means

Details Specific binding assay method and reagent means Specific binding assay method and reagent means

1977-05-10

1980-06-03

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

23910, 23915, 252408, 424 12, G01N 3316

Patent

active

042059526

ABSTRACT:
A method and reagent means for the determination of small quantities of chemical compounds in man, animal and plants by a specific binding assay technique.
The method involves the utilization of a labelling constituent comprising a conjugate of a labelling substance and a binding component said labelling substance being one or more metal atoms which can be easily determined. The labelling constituents are selected from various metalo organic derivatives or metal coordination complexes.
The method is very specific and sensitive and can be successfully utilized for the determination of haptens selected from various groups such as alkaloids, barbiturates, steroids, cannabinoids, vitamins, aminoacids, tranquilizers, sugars, penicillins, etc.

REFERENCES:
patent: 3899298 (1975-08-01), Szczesniak
patent: 3966556 (1976-06-01), Rubenstein
patent: 4022876 (1977-05-01), Anbar
patent: 4036823 (1977-07-01), Soares
Chemical Abstracts, 75: 61339n (1971).
Hackh's Chemical Dictionary, J. Grant, ed., 4th Edition, p. 264, McGraw-Hill, New York, 1969.

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