Specific binding analytical and separation methods using carboxy

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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436531, 436532, 436533, 436534, 436536, 436538, 436541, 436804, 436814, 436817, 436818, 436824, 435 6, 435 722, 435 732, 435 734, 435 79, 435 792, 435 793, 435 794, 5263171, 5263184, 526301, 526314, 530412, 530413, G01N 83545, G01N 33546, G01N 33547

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052622975

ABSTRACT:
Specific binding methods are used for diagnostic assays and purification separations whereby the specific binding capture reagent is prepared from copolymers having highly reactive carboxy groups. These groups are extended from the polymer surface with a linking group having from 8 to 50 atoms in the chain and two or more alkylene, arylene, alkylenearylene or arylenealkylene groups. To these reactive groups is attached a biologically active substance such as a protein or oligonucleotide which then participates in the diagnostic assays or purification separation methods.

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