Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-03-08
1989-11-07
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436542, 436548, 436800, 436804, 436811, 436815, 436518, 436531, 435 68, 4351722, 43524027, 935110, 530387, 530809, G01N 33577, G01N 33569
Patent
active
048792160
ABSTRACT:
The present invention provides a specific antibody against heart muscle light chains (HMLC) with a cross-reactivity against skeletal muscle light chains (SMLC) of less than 5%. The present invention also provides a process for the preparation of this specific antibody, wherein a mammal is immunized with HMLC I and/or HMLC II and the crude serum is recovered and subjected to an immunosorptive purification on an SMLC immune adsorbent based on silicate. Furthermore, the present invention provides a reagent for the determination of HMLC which contains antibodies against HMLC according to the present invention.
REFERENCES:
Haber, E. et al., J. Mol. Cell. Cardiol., 14, Suppl. 3, 139-146, (1982).
Shimizu, T. et al., J. Mol. Biol., 183(2), 271-82, (1985).
Chemical Abstracts, I, 98:103675b, (1983).
Chemical Abstracts, II, 103:139193d, (1985).
Hallermayer Klaus
Katus Hugo
Looser Siegfrid
Boehringer Mannheim GmbH
Nucker Christine M.
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