Specific antibodies against the DNA-binding domain of and immuno

Details Specific antibodies against the DNA-binding domain of and immuno Specific antibodies against the DNA-binding domain of and immuno

1991-11-01

1994-05-17

Wax, Robert A.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

53038822, 5303871, 5303879, 5303881, 43524026, C07K 1528, C12N 512

Patent

active

053127528

ABSTRACT:
The present invention provides unique prepared immunogens, site-specific polyclonal antisera and monoclonal antibodies against the DNA-binding domain of estrogen receptor protein, and immunoassay to determine the functional status of estrogen receptors in a cellular sample. Collectively or individually the component parts of the invention provide the ability not only to identify accurately the presence of human estrogen receptor but also the capability of determining whether the estrogen receptor exists in a functional or non-functional state.

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