Species-specific genetic identification of Mycobacterium paratub

Details Species-specific genetic identification of Mycobacterium paratub Species-specific genetic identification of Mycobacterium paratub

1998-06-30

1999-11-16

Myers, Carla J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 231, 536 237, 536 243, 536 2432, 536 2433, C12Q 168, C12P 1934, C07H 2102, C07H 2104

Patent

active

059855762

ABSTRACT:
An M. paratuberculosis gene referred to as hspX provides a useful target region for the construction of suitable probes and primers that are species-specific for distinguishing M. paratuberculosis from related mycobacteria in a test sample. M. paratuberculosis is the causative agent of Johne's disease and has been isolated from human patients with Crohn's disease.

REFERENCES:
patent: 5314801 (1994-05-01), Nycz et al.
Ellingson, J.L.E. et al. Identification of a gene unique to Mycobacterium avium subspecies paratuberculosis and application to diagnosis of paratuberculosis. Mol. Cell. Probes 12:133-142, Jun. 1, 1998.
Jay L. E. Ellingson et al., "Identification of a Genetic Element Unique to Mycobacterium paratuberculosis and Application to Paratuberculosis Diagnosis" 97th General Meeting, American Society for Microbiology, Miami Beach, May 4-8, 1997.
Jay L. E. Ellingson et al., "Identification of a New Genetic Element Unique to Mycobacterium paratuberculosis and Application to Diagnosis of Paratuberculosis", First International Veterinary and Diagnostics Conference, Madison, Wisconsin, Jul. 27-31, 1997.

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