SPE-4 peptides

Details SPE-4 peptides SPE-4 peptides

1997-01-24

2000-02-01

Caputa, Anthony C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4241851, 4241841, 4241921, 4241931, 4241941, 530300, 530350, 530326, 530327, 5303871, C07K 700, A61K 3900

Patent

active

060199741

ABSTRACT:
This application discloses SPE-4 related peptides, peptide-carrier protein conjugates and fusion proteins, immunogenic compositions, antibodies and methods for characterizing the SPE-4 related protein profiles, useful in diagnosing or monitoring SPE-4 related protein profiles of nematodes and/or Alzheimer's disease patients, either in postmortem tissue, preferably from the frontal cortex of the brain, or from other tissue samples, including without limitation muscles and peripheral blood or in a tissue samples of a living patient, where the tissue analyzed can includes brain, muscle or peripheral blood cells.

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Harlow et al. Antibodies, A Laboratory Manual 1980, Chapter 5, pp. 78-79.
Arduengo et al. Molecular Biology of the Cell Thirty-fourth annual meeting of the American-Society for cell biology, Dec. 10-14, 1994., 5 (Suppl), 1994, 219A, Abstract No. 1275.
Goate et al., (1991) Nature 349:704-706.
L'Hernault et al. (1992) J. Cell Biol. 119:55-68.
Levitan and Greenwald (1995) Nature 377:351-354.
Okamoto and Thomson (1985) J. Neurosci 5:643-653.
Saunders et al. (1993) Neurology 43:1467-1472.
Schellenberg et al. (1992) Science 258:668-671.
Sherrington et al. (1995) Nature 375:754-760.
Strittmatter et al. (1993) Proc. Natl. Acad. Sci. USA 90:1977-1981.

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