Spatial evolution of neural activity

Details Spatial evolution of neural activity Spatial evolution of neural activity

2004-06-18

2010-02-09

Jones, D L (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Testing efficacy or toxicity of a compound or composition

C424S009100, C424S001110

Reexamination Certificate

active

07658912

ABSTRACT:
A method for identifying a candidate drug includes administering a test compound to test subjects and having the test subjects perform a sustained task. A first evolution of neural activity in the test subjects is then determined and compared with a second evolution of neural activity. This second evolution of neural activity is obtained from control subjects performing the sustained task in the absence of the test compound. The test compound is then designated to be a candidate drug when a difference between the first and second evolutions of neural activity is above a difference threshold.

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