Sparsely cross-linked nanogels: a novel polymer structure...

Details Sparsely cross-linked nanogels: a novel polymer structure... Sparsely cross-linked nanogels: a novel polymer structure...

2008-07-15

2008-07-15

Harlan, Robert D. (Department: 1796)

Chemistry: electrical and wave energy

Processes and products

Electrophoresis or electro-osmosis processes and electrolyte...

C204S469000, C204S606000

Reexamination Certificate

active

07399396

ABSTRACT:
The present invention is generally directed to novel polymeric mateirals for use in the electrophoretic separation of nucleic acids. In particular, the novel polymer materials are sparsely crosslinked nanogels, dissolved in an aqueous buffer to form solutions with moderate to high viscosity. The present invention further provides methods for generating such novel polymers, and related methods of their use.

REFERENCES:
patent: 5213669 (1993-05-01), Guttman
patent: 5296116 (1994-03-01), Guttmann
patent: 5332481 (1994-07-01), Guttman
patent: 5370777 (1994-12-01), Guttman et al.
patent: 5421980 (1995-06-01), Guttmann
patent: 5873991 (1999-02-01), Gothe et al.
patent: 6333051 (2001-12-01), Kabanov et al.
patent: 6696089 (2004-02-01), Kabanov et al.
Slater, G. W., Noolandi, J. Biopolymers 1986, 25, 431-454.
Goetzinger W., et al., Electrophoresis 1998 1, 242-248.
Barron, A. E., et al. Electrophoresis 1996, 17, 744-757.
Chairi, M., et al. Electrophoresis 1994, 15, 177-186.
Gelfi, C., et al. Electrophoresis 1996, 17, 738-743.
Albarghouthi, M., Barron, A. E. Electrophoresis 2000, 21, 4096-4111.
Madabhushi, R. S., et al. Electrophoresis 1997, 18, 104-111.
Madabhushi, R. S., et al., Electrophoresis 1998, 19, 224-230.
Duke, T., et al. Biopolymers 1994, 34, 239-247.
Cottet, H., et al. Electrophoresis 1998, 19, 2151-2162.
Arshady, R., Colloid Polym. Sci. 1992, 270 (8), 717-732.
Hunkeler, D., Polym. Int. 1992, 27 (1), 23-33.
Baade, W., Reichert, K. H., Eur. Polym. J. 1984, 20, 505-512.
Pelton, R. Adv. Colloid Interface Sci. 2000, 85, 1.
McAllister, K.; et al., J. JACS 2002, 124, 15198.
Heiger, D. N., et al. Chromatogr. 1990, 33-48.
Guttman, A., et al. Anal Chem. 1990, 62 (2), 137-141.
Harke, H. R., et al. J. Chromatogr. 1992, 608, 143-150.
Smith, L. M. Nature 1991, 349 (6312), 812-813.
Drossman, H., et al. Analytical Chemistry 1990, 62 (9), 900-903.
Luckey, J. A., et al. Nucleic Acids Research 1990, 18 (15), 4417-4421.
Baba, Y., et al. Anal Chem. 1992, 64 (11), 1221-1225.
Bae, Y. C., et al. J. Chromatogr. A 1993, 652, 17-22.
Ruiz-Martinez, M. C., et al. Anal. Chem. 1993, 65, 2851-2858.
Cohen, A. S., et al. Journal of Chromatography 1990, 516 (1), 49.
Fung, E. N., et al. Anal. Chem. 1995, 67 (13), 1913-1919.
Gao, Q. F., et al. Anal. Chem. 1998, 70 (7), 1382-1388.
Salas-Solano, O., et al. Anal. Chem. 1998, 70 (19), 3996-4003.
Albarghouthi, M. N., et al. Electrophoresis 2001, 22, 737-747.
Albarghouthi, M. N., et al. Electrophoresis 2002, 23 (10), 1429-1440.
Buchholz, B. A., et al. Anal. Chem. 2001, 73, 157-164.
Heller, C., et al. Electrophoresis 1999, 20, 1962-1977.
Carrilho, E., et al. Anal. Chem. 1996, 68 (19), 3305-3313.
Zhou, H., et al. Anal. Chem. 2000, 72 (5), 1045-1052.
Ugaz, V. M., et al. Electrophoresis 2002, 23 (16), 2777-2787.
Hunkeler, D. J., Macromolecules 1991, 24 (9), 2160.
Sakai, T., Yoshida, R. Langmuir 2004, 20, 1036.
Jones, C., Lyon, A. Macromolecules 2003, 36, 1988.
Lu, X., Hu, Z., Gao, J. Macromolecules 2000, 33, 8698.
Zhou, S., Chu, B. J. Phys. Chem. B 1998, 102, 1364.
Ogawa, K.; Nakayama, A.; Kokufuta, E. Langmuir 2003, 19, 3178.
Kazakov, S.; Kaholek, M.; Teraoka, I.; Levon, K. Macromolecules 2002, 35, 1911.
Oh, K.; Oh, J.; Choi, H.; Bae, Y. Macromolecules 1998, 31, 7328.
Berndt, I.; Richtering, W. Macromolecules 2003, 36, 8780.
Ito et al., E. Langmuir 1999, 15, 4289.
Idziak, I.; Avoce, D.; Lessard, D.; Gravel, D.; Zhu, X. Macromolecules 1999, 32, 1260.
Siu, M.; Liu, H.; Zhu, X.; Wu, C. Macromolecules 2003, 36, 2103.
Liang, D., et al., 1999 Macromolecules 32: 6326-63332.
Sudor, J., et al., 2001 Electrophoresis 22: 720-728.
Liu, T., et al., 2001 Electrophoresis 22: 449-458.

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