Sos1 inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C536S023100, C536S024100, C435S006120, C514S04400A

Reexamination Certificate

active

10609150

ABSTRACT:
Inhibitors of human Sos1, including antisense oligonucleotides, methods, and compositions specific for human Sos1, are provided. Methods of using the compositions for modulating Sos1 expression and for regulating cell growth, particularly tumor cell growth, are also provided.

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patent: WO 93/21314 (1993-10-01), None
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Sibilia, M. et al.,The EGF Receptor Provides an Essential Survival Signal for SOS-Dependent Skin Tumor Development, CELL 102:211-220, 2000.
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Chin, Andrew, CD-ROM document, entitled “On the Preparation and Utilization of Isolated and Purified Oligonucleotides,” including copy of letter, dated May 12, 2005 from Andrew Chin.

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