Sorting device for biological cells or viruses

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

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Details

422 58, 422 8205, 422 8208, 435808, 4352887, 209 31, 209567, 209576, 209155, 209906, G01N 3300

Patent

active

058372008

ABSTRACT:
The sorting device is able to sort biological objects, particularly cells or viruses, in liquids as a function of physically measurable criteria or properties. The sorting apparatus is provided with a feed inlet (1) for the biological liquid which branches into a microstructured system of multi-parallel main channels (3) and sorting modules (4) each with a switch unit for distribution to two different outlet channels (19,20). Inside a sorting module (4), at least one sensor (9,10) is arranged on each main channel, and a sorting actuator (12) controlled by the relevant sensor is arranged on each switch unit (11). Finally, each outlet channel (20) is connected to a collecting channel (6) for the unselected biological cells or viruses, and each outlet channel (19) is connected to a collecting channel (5) for the selected cells or viruses. If the cells or viruses are magnetically marked, it is possible to dispense with the sensor (9,10) on the main channels (3). In that case, the sorting actuators arranged on the switch units are designed as magnetic deflection modules (37,38). In this case, the magnetic deflection modules undertake direct classification or selection as a function of the magnetic properties of the biological objects to be sorted.

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