Sorbitan esters as skin permeation enhancers

Details Sorbitan esters as skin permeation enhancers Sorbitan esters as skin permeation enhancers

1992-04-21

1993-05-18

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514777, 514946, 514947, 424449, 536119, A01N 4538

Patent

active

052121992

ABSTRACT:
Skin permeation enhancer compositions are provided which increase the permeability of skin to transdermally administered pharmacologically active agents. The compositions contain a sorbitan ester in addition to the selected pharmacologically active agent, and may also contain a C.sub.1 -C.sub.4 aliphatic alcohol. Methods and transdermal drug delivery systems for using the compositions are also provided.

REFERENCES:
patent: 4685911 (1987-08-01), Konno et al.
patent: 5122383 (1992-06-01), Heiber et al.

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