Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr

Details Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr

1982-11-10

1984-03-06

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549404, C07D491107, C07D31168

Patent

active

044355785

ABSTRACT:
Sorbinil is obtained by cyclization of S-6-fluoro-4-ureidochromane-4-carboxylic acid, which is in turn obtained by resolution of racemic 6-fluoro-4-ureidochroman-4-carboxylic acid via diasteromeric salts with either D-(+)-(1-phenethyl)amine or L-(-)-ephedrine.

REFERENCES:
patent: 4117230 (1978-09-01), Sarges
patent: 4130714 (1978-12-01), Sarges
patent: 4286098 (1981-08-01), Sarges
patent: 4348526 (1982-09-01), Sarges

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