Sorbent for saccharides, glycoproteins and polyesters comprising

Details Sorbent for saccharides, glycoproteins and polyesters comprising Sorbent for saccharides, glycoproteins and polyesters comprising

1982-04-16

1984-05-01

Kight, III, John

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

2105021, 435174, 435179, 435181, C12N 1116, C12N 1112, C12N 1106

Patent

active

044462751

ABSTRACT:
The invention relates to selectively acting polymeric sorbents or saccharides, glycoproteins and saccharide containing polymers. In accordance with the invention, lectins are covalently bonded on vehicles selected from among, oxidized glycosylated hydroxyalkylacrylates or hydroxyalkylmethacrylates, and polyvinyl alcohol. These vehicles are comparable to known materials based on polysaccharides with bonded-on lectins, especially as far as the absorption power of the sorbent is concerned. The preferred process for preparing such sorbents is substantially easier than the hitherto used ones since it does not require specific measures to be taken in the work with highly toxic activating agents, and enables a simple control of conversion degree of the bonding reaction while achieving a relatively high reproducibility. Apart from this, unoxidized saccharide molecules bonded on the vehicle make it hydrophilic, or at least raise its original hydrophility.

REFERENCES:
patent: 3914183 (1975-10-01), Johansson et al.
patent: 3947352 (1976-03-01), Cuatrecasas et al.
patent: 4038140 (1977-07-01), Jaworek et al.
Acta Chem. Scand., vol. 24, No. 5, 1970/pp. 1839-1841, short communication, Aspberg, K.ang.re et al., "Group Specific Adsorption of Glycoproteins".

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