Sorbent families

Details Sorbent families Sorbent families

1996-07-31

1998-09-01

Hutzell, Paula K.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Separation or purification

530329, A61K 3808, C01K 700

Patent

active

058012257

ABSTRACT:
Compounds useful as affinity chromatography supports and as labeled reagents are disclosed. The compounds are peptides which can be constituted in families of positively charged, negatively charged or uncharged small peptides or the amidated forms thereof with varying characteristics as to charge, charge distribution, hydrophobicity, cyclization, and helical conformation propensity.

REFERENCES:
patent: 4694044 (1987-09-01), Kiniwa
patent: 4963263 (1990-10-01), Kauvar
Marshall, "Three-Dimensional Structure of Peptide-Protein Complexes: Implications for Recognition" Current Opinion in Structural Biology 2:904-919 (1992).
Muller, et al., "New Ion Exchangers for the Chromatography of Biopolymers" Journal of Chromatography 510:133-140 (1990).
Ohlson, et al., "Novel Approach to Affinity Chromatography Using `Weak` Monoclonal Antibodies" Analytical Biochemistry 169:204-208 (1988).

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