Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1998-01-23
2000-07-18
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
4353201, 435325, 4352523, 536 232, C12N 900, C12N 1500, C12N 500, C12N 120, C07H 2104
Patent
active
060906014
ABSTRACT:
Domains of epothilone polyketide synthase, and polynucleotides encoding therefor. Additionally, chimeric polyketide synthases that include domains, or subsets of domains, patterned on epothilone polyketide synthase. Methods to prepare epothilone in pharmaceutically useful quantitites are described, as are methods to prepare polyketide combinatorial libraries.
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Betlach Mary C.
Gustafsson Claes
Favorito Carolyn
Kaster Kevin
Kosan Bioscience
Monshipouri M.
Murashige Kate H.
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