Sonication to selectively lyse different cell types

Details Sonication to selectively lyse different cell types Sonication to selectively lyse different cell types

2004-09-17

2009-06-02

Lankford, Leon B. (Department: 1651)

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Cell membrane or cell surface is target

C435S259000, C435S306100, C435S252400

Reexamination Certificate

active

07541166

ABSTRACT:
A sonication apparatus is directed to a microfluidic-based system to automate differential extraction of specific cell types within a mixed sample. The microfluidic-based system includes a sonication module for selective cell lysis, separating means to eliminate centrifugation, high surface area pillar chip modules to purify DNA from a cell lysate, and microfluidic circuitry to integrate the steps in an automated platform.

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