Some macrocyclic compounds and their preparation

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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549 11, 549263, 330299, C07D25702, C07D32300, C07D34100

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active

045900051

ABSTRACT:
The present invention relates to novel macrocyclic carbonyl compounds of the macrocyclic carbamate and lactone type, to chiral macrocyclic structures, to macrocyclic urea compounds and to macrocyclic thiolactones and to a process for the preparation of same. The process of the invention comprises reacting a stannoxane, silazane or silathiane compound with an activated carbonyl compound in an organic solvent at moderate temperature.

REFERENCES:
patent: 3987061 (1976-10-01), Pedersen
patent: 4165321 (1979-08-01), Harris et al.
patent: 4251448 (1981-02-01), Bauer et al.
Shanzer et al., "Tetrahedron Letters" (1979) pp. 5019-5020.
Shanzer et al., "J. Chem. Soc., Chem. Communications" (1980) pp. 176-177.
Shanzer et al., "J.C.S. Chem. Comm." (1980) pp. 259-260.
Shanzer et al., "J.C.S. Chem. Comm." (1981) pp. 634-635.
Shanzer et al., "Angewandte Chemie", vol. 19, No. 4, Apr. 1980, pp. 326-327.
Shanzer et al., "J. Am. Chem. Soc.", vol. 81, pp. 7339-7340 (1981).
Shanzer et al., "Synthesis with Tin Templates: The Preparation of Macrocyclic Tetralactones" (no date).
Shanzer et al., "Catalytic Preparation of Macrocyclic", `Crown Lactones` (no date).

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