Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-07-07
1999-12-07
Johnson, Nancy A
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 72, 435 723, 435 75, 435 79, 435 791, 435 792, 436 63, 436 64, 436547, 4241841, 4241851, 4241921, 4241931, 4242781, 530300, 530325, 530326, 530350, 5303871, 5303879, 530403, 530413, G01N 3553, C07K 1628, C07K 14705, C07K 1447
Patent
active
059981547
ABSTRACT:
Peptide antigens derived from the carboxy terminus of somatostatin receptors and antibodies produced using the peptide antigens. The anti-somatostatin receptor antibodies are specific for a receptor subtype and are useful in characterizing receptor subtypes expressed by tissues.
REFERENCES:
patent: 5331094 (1994-07-01), Eppler et al.
Bell, Graeme I. et al. (1995) "Molecular Biology of Somatostatin Receptors" in 1995 Somatostatin and its receptors. Wiley, Chichester Ciba Foundation Symposium, p. 65-88.
Berelowitz, Michael et al. (1995) "Regulation of Somatostatin Receptor mRNA Expression" in 1995 Somatostatin and its receptors. Wiley, Chichester Ciba Foundation Symposium, p. 111-126.
Birnbaumer, Lutz et al. (1990) "Receptor-effector Coupling by G Proteins" Biochimica et Biophysica Acta, 1031:163-224.
Brown, Patricia J. et al. (1990) Identification of Somatostatin Receptors by Covalent Labeling with a Novel Photoreactive Somatostatin Analog' The Journal of Biological Chemistry 265(29):17995-18004.
Brown, Patricia J. and Schonbrunn, Agnes (1993) "Affinity Purification of a Somatostatin Receptor-G-protein Complex Demonstrates Specificity in Receptor-G-protein Coupling" The Journal of Biological Chemistry 268(9):6668-6676.
Brown, P. J. et al. (1993) "Selective Immunoprecipitation of Somatostatin Receptor Subtype 1 (SSR1) with an Antipeptide Antibody" In The Proceedings of the 75th Meetings of the Endocrine Society, p. 410.
Bruno, John F. (1992) "Molecular Cloning and Functional Expression of a Brain-Specific Somatostatin Receptor" Proc. Natl. Acad. Sci. USA 89:11151-11155.
Bruns, Christian et al. (1994) "Molecular Pharmacology of Somatostatin-receptor Subtypes" Annals of the NY Acad. Sci 733:138-146.
Bruns, Ch. et al. (1995) "Characterization of Somatostatin Receptor Subtypes" in 1995 Somatostatin and its receptors. Wiley, Chichester Ciba Foundation Symposium, p. 89-110.
Carlson, G. L., et al. (1994) "Somatostatin in Gastroenterology" BMJ 309:604-605.
Coy, David H. et al. (1995) "Somatostatin Analogues and Multiple Receptors: Possible Physiological Roles" in 1995 Somatostatin and its receptors. Wiley, Chichester Ciba Foundation Symposium, p. 240-254.
Estes, Heather G. (1992) "At Least Three Distinct Proteins are Necessary for the Reconstitution of a Specific Multiprotein Complex at a Eukaryotic Chromosomal Origin of Replication" Proc. Natl. Acad. Sci. USA 89:11156-11160.
Ezzat, Shereen and Shlomo Melmed (1992) "Endocrine Applications of the Somatostatin Analogue Octreotide (Sandostatin.RTM.)" Metabolism 41(9)suppl 2:34-38.
Gu, Yi-Zhong et al. (1995) "Distribution and G Protein Coupling of Somatostatin Receptor 2A (SSTR2A) Characterized by a Receptor Specific Antibody" In The Proceedings of the 77th Meetings of the Endocrine Society, p. 90.
Guillemin, Roger (1993) "Somatostatin: The Early Days" Digestion 54(suppl 1):3-6.
Harlow, Ed and David Lane (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory.
Harris, A. G. and S.P. Kokoris (1993) "Applications Therapeutiques de la Somatostatine et de Son Analogue, l'Octreotide" La Presse Medicale 22(15):724-733.
Hershberger, Ray E. et al (1994) "The Somatostatin Receptors SSTR1 and SSTR2 Are Coupled to Inhibition of Adenylyl Cyclase in Chinese Hamster Ovary Cells via Pertussis Toxin-Sensitive Pathways" Endocrinology 134(3):1277-1285.
Hoyer, Daniel et al. (1994) "Molecular Pharmacology of Somatostatin Receptors" Naunyn-Schmiedeberg's Archives of Pharmacology 350:441-453.
Hoyer, D. et al. (1995) "Classification and Nomenclature of Somatostatin Receptors" TiPS 16:86-88.
Hurst, Roger D. et al. (1993) "Use of Radiolabeled Somatostatin Analogs in the Identification and Treatment of Somatostatin Receptor-Bearing Tumors" Digestion 54(suppl 1):88-91.
Kimura, Nobuko (1989) "Developmental Change and Molecular Properties of Somatostatin Receptors in the Rat Cerebral Cortex" Biochemical and Biophysical Research Communications 160(1):72-78.
Kimura, Nobuko et al. (1989) "Characterization of 17-.beta.-Estradiol-Dependent and -Independent Somatostatin Receptor Subtypes in Rat Anterior Pituitary" The Journal of Biological Chemistry 264(12):7033-7040.
Kluxen, Franz-Werner (1992) "Expression Cloning of a Rat Brain Somatostatin Receptor cDNA" Proc. Natl. Acad. Sci. USA 89:4618-4622.
Krenning, E. P. et al. (1993) "In-Octreotide Scintigraphy in Oncology" Digestion 54(suppl 1):84-87.
Kvols, L. K. et al. (1992) "The Presence of Somatostatin Receptors in Malignant Neuroendocrine Tumor Tissue Predicts Responsiveness to Octreotide" The Yale Journal of Biology and Medicine 65:505-518.
Laemmli, U. K. (1970) "Cleavage of Structural Proteins During the Assembly of the Head of Bacteriophage T4" Nature 227:680-685.
Lamberts, Steven W. J. (1993) "Validation of Somatostatin Receptor Scintigraphy in the Localization of Neuroendocrine Tumors" Acta Oncologica 32(2):167-170.
Lamberts, S. W. J. et al. (1995) "Somatostatin Receptors: Clinical Implications for Endocrinology and Oncology" in 1995 Somatostatin and its receptors. Wiley, Chichester Ciba Foundation Symposium, p. 222-239.
Lerner, Richard A. et al. (1981) "Chemically Synthesized Peptide Predicted from the Nucleotide Sequence of the Hepatitis B Virus Genome Elicit Antibodies Reactive with the Native Envelope Protein of Dane Particles" Proc. Natl. Acad. Sci. USA 78(6):3403-3407.
Le Romancer, Muriel et al. (1994) "The 86-kDa Subunit of Autoantigen Ku Is A Somatostatin Receptor Regulating Protein Phosphatase-2A Activity" The Journal of Biological Chemistry 269(26):17464-17468.
Marbach, P. et al. (1993) "From Somatostatin to Sandostatin.RTM.: Pharmacodynamics and Pharmacokinetics" Digestion 54(suppl 1):9-13.
Merrifield, R. B. (1963) "Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide" Journal of the American Chemical Society 85:2149-2154.
Merrifield, R. B. et al. (1982) Synthesis of the Antibacterial Peptide Cecropin A(1-33) Biochemistry 21:5020-5031.
Meyerhoff, W. et al. (1992) "Molecular Cloning of a Somatostatin-28 Receptor and Comparison of Its Expression Pattern with that of a Somatostatin-14 Receptor in Rat Brain" Proc. Natl. Acad. Sci. USA 89:10267-10271.
Moore, William T. (1991) "Monitoring Peptide Synthesis Stepwise by Mass Spectrometry" Techniques in Protein Chemistry II, Chapter 49, pp. 511-528.
Nakabayashi, Itsuko O. and Nakabayashi, Hajime (1992) Monoclonal Antibodies to Somatostatin Receptor of Rat Brain 11(6):789-794.
O'Carroll, Anne-Marie et al. (1992) "Molecular Cloning and Expression of a Pituitary Somatostatin Receptor with Preferential Affinity for Somatostatin-28" Molecular Pharmacology 42:939-946.
Patel, Yogesh C. et al. (1994) "Expression of Multiple Somatostatin Receptor Genes in AtT-20 Cells" The Journal of Biological Chemistry 269(2):1506-1509.
Pless, J. (1993) "From Somatostatin to Sandostatin.RTM.: History and Chemistry" Digestion 54(suppl 1):7-8.
Pollak, M. et al. (1992) "Potential Role for Somatostatin Analogues in Breast Cancer: Rationale and Description of an Ongoing Trial" Metabolism 41(9)suppl 2:119-120.
Presky, David H. (1988) "Iodination of [Tyr.sup.11 ]Somatostatin Yields a Super High Affinity Ligand for Somatostatin Receptors in GH.sub.4 C.sub.1 Pituitary Cells" Molecular Pharmacology 34:651-658.
Prevost, Gregoire, et al. "Receptors for Somatostatin and Somatostatin Analogues in Human Breast Tumors" in Annals New York Academy of Sciences, pp. 147-154.
Reyl-Desmars, Florence (1989) "Solubilization and Immunopurification of a Somatostatin Receptor from the Human Gastric Tumor Cell Line HGT-1" The Journal of Biological Chemistry 264(31):18789-18795.
Reubi, J. C. (1990) "Detection of Somatostatin Receptors in Surgical and Percutaneous Needle Biopsy Samples of Carcinoids and Islet Cell Carcinomas" Cancer Research 50:5969-6977.
Reubi, Jean-Claude (1992) "Somatostatin Receptors in the Gastrointestinal Tract in Health and Disease" The Yale Journal of Biology and Medicine 65:493-503.
Reubi, J. C. (1992) "In Vitro Detection of Somatostatin Receptors in Human Tumors" Metabolism 41(9)Suppl 2:104-110.
Reubi, J. C. (1993) "In Vitro Detection of Somatostatin Receptors in Hum
Johnson Nancy A
The University of Texas System
LandOfFree
Somatostatin receptor peptide antigens and antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Somatostatin receptor peptide antigens and antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Somatostatin receptor peptide antigens and antibodies will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-822482