Somatostatin-dopamine chimeric analogs

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence

Reexamination Certificate

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C530S327000, C530S329000, C530S330000, C530S311000, C530S345000

Reexamination Certificate

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07579435

ABSTRACT:
Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo. An example is: 6-n-propyl-8β-ergolinglmethylthioacetyl-D-Phe-c-(Cys-Tyr-D-Trp-Lys-Abu-Cys)-Thr-NH2.

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English language Abstract for International Application No. WO 00/04018 published Jan. 27, 2000.

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