Somatostatin-derived peptides for imaging and therapeutic uses

Details Somatostatin-derived peptides for imaging and therapeutic uses Somatostatin-derived peptides for imaging and therapeutic uses

1995-06-06

1998-10-13

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to lymphokine, cytokine, or other secreted growth...

424 169, 424 153, 530311, 514806, 930160, A61K 5108, A61K 3831, C07K 500

Patent

active

058208453

ABSTRACT:
This invention relates to therapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labeled radiodiagnostic agents. Specifically, the invention relates to peptide derivatives and analogs of somatostatin, and embodiments of such peptides labeled with technetium-99m (Tc-99m), as well as methods and kits for making, radiolabeling and using such peptides to image sites in a mammalian body. The invention also relates to peptide derivatives and analogues of somatostatin labeled with rhemium-186 (.sup.186 Re) and rhenium-188 (.sup.188 Re), and methods and kits for making, radiolabeling and using such peptides therapeutically in a mammalian body.

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