Somatostatin analogs with dissociated biological activities

Details Somatostatin analogs with dissociated biological activities Somatostatin analogs with dissociated biological activities

1977-04-07

1979-01-09

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

2601125S, C08L 3700, C07C10352

Patent

active

041337824

ABSTRACT:
The present invention relates to peptides having dissociated biological activity in respect to the inhibition of growth hormone, insulin, and glucagon secretion. The peptides are analogs of somatostatin.

REFERENCES:
M. Brown, et al., Chem. Abst. 86, 1977, p. 65892n.
J. Rivier, et al., J. Med. Chem. 18, 1975, pp. 123-126.
M. Brown, et al., Endocrinology 98, 1976, pp. 336-343.
J. Rivier, et al., J. Med. Chem. 19, 1976, pp. 1010-1013.
J. Rivier, et al., Biochem. and Biophys. Res. Commun. 65, 1975, pp. 746-751.
C. Meyers, et al., Biochem. and Biophys. Res. Commun. 74, 1977, pp. 630-636.

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