Somatostatin analogs and intermediates thereto

Chemistry of carbon compounds – Miscellaneous organic carbon compounds

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Details

26011255, 424177, C07C10352, C08L 8900, A61K 3700

Patent

active

040873900

ABSTRACT:
The tetradecapeptides ##STR1## in which Y is L-Asn or L-Ala are described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the tetradecapeptides. These tetradecapeptides as well as their pharmaceutically-acceptable acid addition salts exhibit various activities including inhibition of the release of gastric acid.

REFERENCES:
rivier, J. et al, (1975) Biochem, Biophys., Re., Comm., 65:746-751.

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