Somatostatin analogs and intermediates thereto

Details Somatostatin analogs and intermediates thereto Somatostatin analogs and intermediates thereto

1976-07-28

1977-12-06

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

2601125S, C08L 6700, C07C10352

Patent

active

040616070

ABSTRACT:
The tetradecapeptides ##STR1## in which Y is L-Cha, L-Leu, or D-Phe are described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the tetradecapeptides. These tetradecapeptides as well as their pharmaceutically-acceptable acid addition salts inhibit the release of growth hormone.

REFERENCES:
J.A.C.S., (1974), pp. 2986-2992, vol. 96.

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