Somatostatin analogs and intermediates thereto

Details Somatostatin analogs and intermediates thereto Somatostatin analogs and intermediates thereto

1977-02-02

1978-06-06

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

2601125S, 424177, C08L 3700, C07C10352, A61K 3700

Patent

active

040935744

ABSTRACT:
The tetradecapeptides ##STR1## in which Y is L-Asn or L-Ala are described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the tetradecapeptides. These tetradecapeptides as well as their pharmaceutically-acceptable acid addition salts exhibit various activities including inhibition of the release of gastric acid.

REFERENCES:
rivier; J. et al. (1975) J. Med. Chem., 18: 123-126.

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