Somatostatin agonists

Details Somatostatin agonists Somatostatin agonists

2007-12-25

2007-12-25

Bragdon, Kathleen Kerr (Department: 1656)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Lutenizing hormone releasing factor ; related peptides

C530S317000, C530S328000, C514S011400, C514S016700, C514S009100

Reexamination Certificate

active

10474248

ABSTRACT:
Claimed are a series of somatostatin agonists and uses thereof, according to formula (I),in-line-formulae description="In-line Formulae" end="lead"?A1-cyclo[Cys-A2-D-Trp-A3-A4-Cys]-A5-Y1,   (I)in-line-formulae description="In-line Formulae" end="tail"?wherein A1, A2, A3, A4, A5and Y1are as defined in specification provided that the amine nitrogen of at least one peptide bond is substituted with a methyl group or pharmaceutically acceptable salts thereof.

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