Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles
Patent
1994-12-28
1996-03-26
Brust, Joseph Paul
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitriles
C07C25330
Patent
active
055022359
ABSTRACT:
A process for making 2,6-difluorobenzonitrile, comprising reacting 2,6-dichlorobenzonitrile with a substantially anhydrous metal fluoride at a temperature between about 160.degree. C. and about 300.degree. C. and in the presence of a phase transfer catalyst, which is typically a polyether, tetra-substituted phosphonium salt, tetra-substituted ammonium salt, and cryptand, but in the absence of a solvent. After taking off the product the resulting mixture may be recycled into the reactor for the next reaction cycle. Upon build-up of tars in the reaction process, the invention includes the separation of catalyst from the tars and the recycle thereof.
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Leng Ronald B.
Tobey Richard E.
Zettler Mark W.
Borucki Andrea T.
Brust Joseph Paul
DowElanco
Knauer Richard T.
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