Measuring and testing – Liquid analysis or analysis of the suspension of solids in a... – Content or effect of a constituent of a liquid mixture
Patent
1974-07-22
1976-01-27
Queisser, Richard C.
Measuring and testing
Liquid analysis or analysis of the suspension of solids in a...
Content or effect of a constituent of a liquid mixture
210198C, 417536, G01N 3108
Patent
active
039344568
ABSTRACT:
Solvent gradient generating apparatus in a liquid column chromatography system. A multi-compartment vessel having an input/output port pair for each compartment is coupled between a high pressure pump and the column cell for providing both gradient generation and pulse damping. A piston, which is slidably contained within the vessel, sealably provides the compartments. Means external to the vessel are provided for controlling the rate of movement of the piston within the vessel. The volume of each compartment is controlled by the position of the piston, and the rate of movement of the piston controls mixing of the solvent components delivered to the column cell. Each compartment has input and output ports. In one embodiment, both input ports are coupled to the high pressure pump while only one output port is coupled to the column cell. In another embodiment, only one input port is coupled to the pump and the other input port and one output port are sealed.
REFERENCES:
patent: 505090 (1893-09-01), Carse
patent: 1498471 (1924-06-01), Miller
patent: 2670683 (1954-03-01), Lundh
patent: 3446057 (1969-05-01), Bakalyar et al.
patent: 3507580 (1970-04-01), Howard et al.
patent: 3701609 (1972-10-01), Bailey
patent: 3830369 (1974-08-01), Pfadenhauer
Cole Stanley Z.
Fisher Gerald M.
Morrissey John J.
Queisser Richard C.
Roskos Joseph W.
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