Solvent front detection method and manufacture

Details Solvent front detection method and manufacture Solvent front detection method and manufacture

1979-09-13

1981-06-09

Adee, John

Liquid purification or separation

Processes

Chromatography

210 85, B01D 1508

Patent

active

042723809

ABSTRACT:
An improved method of thin layer chromatography and articles are provided for the detection of drugs involving extraction, concentration, transfer to a disc, development and detection. The method employs lipophilic dye containing disc shaped inserts impregnated with analytes or one or more standards. The discs are inserted in corresponding hollows on a thin layer chromatographic plate and eluted with a suitable solvent. As the solvent migrates, the dye is eluted from the disc and migrates as a spot with the solvent front which is thus visually developed with the dye.

REFERENCES:
patent: 3046779 (1962-07-01), Coleman
patent: 3598995 (1971-08-01), Inoue et al.
patent: 3714035 (1973-01-01), Jones
patent: 3914174 (1975-10-01), Fuchs
patent: 4126554 (1978-11-01), Rainin

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