Solutions of pentamidine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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A61K 31155

Patent

active

048534161

ABSTRACT:
A pharmaceutical composition comprising an aqueous solution of pentamidine or a pharmaceutically acceptable salt thereof, the solution having a pH of less than 4.5. The pH of the solution is preferably less than 4.0, more preferably less than 3.5, and especially less than 3.0.
Also disclosed is a method for the prophylactic or remedial treatment of pneumo-cystis carinii pneumonia, which method comprises administration by inhalation to a patient having or being susceptible to that condition of a therapeutically effective quantity of an aqueous solution of pentamidine, or a pharmaceutically acceptable salt thereof, the solution having a pH of less than 4.5.

REFERENCES:
Chemical Abstracts 105: 85051b (1986).
Chemical Abstracts 107: 53x (1987).

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