Surgery – Means for introducing or removing material from body for... – Material introduced into and removed from body through...
Patent
1993-06-04
1995-04-18
Yasko, John D.
Surgery
Means for introducing or removing material from body for...
Material introduced into and removed from body through...
604 53, 604 56, A61M 100, A61M 3100
Patent
active
054074282
ABSTRACT:
An artificial plasma-like substance having at least one water soluble polysaccharide oncotic agent selected from the group consisting of high molecular weight hydroxyethyl starch, low molecular weight hydroxyethyl starch, dextran 40 and dextran 70, which is buffered by lactate and has a pre-administration pH of between 4 and 6.5 is disclosed. In one embodiment, the artificial plasma-like solution may have at least two water soluble polysaccharide oncotic agents one of which is eliminated from the circulation slowly and the other of which is eliminated from the circulation quickly. Supplementation of the plasma-like solution with certain ions is described. A system for administration of the plasma-like solution to a subject wherein the system comprises a first and second solution each having particular buffers is described. Methods for the administration of the plasma-like solution are also disclosed.
REFERENCES:
patent: Re34077 (1992-09-01), Segall et al.
patent: 3937821 (1976-02-01), Irikura et al.
patent: 4923442 (1990-05-01), Segall et al.
patent: 5120719 (1992-06-01), Iwamoto et al.
patent: 5130230 (1992-07-01), Segall et al.
Belzer et al., "Combination Perfusion-Cold Storage for Optimum Cadaver Kidney Function and Utilization," Transplantation (1985) 39(2):118-121.
Bishop et al., "Evaluation of Hypertonic Citrate Flushing Solution for Kidney Preservation Using the Isolated Perfused Rat Kidney" Transplantation (1978) 25(5):235-239.
Collins, G. M., "Hypothermic Kidney Storage" Transplant. Proc. (1977) 9:1529-1534.
Fischer et al., "Flush Solution 2, a New Concept for One to Three Day Hypothermic Renal Storage Preservation" Transplantation (1985) 39(2):122-126.
Kallerhoff et al., "Effects of Preservation Conditions and Temperature on Tissue Acidification in Canine Kidneys" Transplantation (1985) 39(5):485-489.
Ross et al., "72 Hour Canine Kidney Preservation Without Continuous Perfusion" Transplantation (1976) 21:498-501.
Sprung et al., "Effects of Acute Hypothermia and .beta.-Adrenergic Receptor Blockade on Serum Potassium Concentration in Rats" Critical Care Medicine (1991) 19(12):1545-1551.
Wall et al., "Simple Hypothermic Preservation for Transporting Human Livers Long Distances for Transplantation" Transplantation (1977) 23:210-216.
Segall Judith M.
Segall Paul E.
Sternberg Hal
Waitz Harold D.
BioTime, Inc.
Bozicevic Karl
Cermak Adam J.
Gregg-Emery Valeta
Yasko John D.
LandOfFree
Solutions for use as plasma expanders and substitutes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Solutions for use as plasma expanders and substitutes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Solutions for use as plasma expanders and substitutes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-64098