Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding...

Details Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding... Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding...

2011-03-22

2011-03-22

Jiang, Dong (Department: 1646)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S130100, C424S134100, C530S350000, C530S351000

Reexamination Certificate

active

07910540

ABSTRACT:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. ZcytoR14 is a common receptor for IL-17A and IL-17F. The present invention includes soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners, as well as methods for antagonizing IL-17F, IL-17A or both IL-17A and IL-17F using such soluble receptors, antibodies and binding partners.

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