Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)

Details Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl) Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)

1995-02-23

1998-08-18

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544325, C07D40302, A61K 31505

Patent

active

057958998

ABSTRACT:
Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)amide, a process for the preparation thereof, the use thereof as pharmaceuticals and starting materials.
Salts, which are soluble and freely soluble in water, of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)-amide and a process for the preparation thereof are described. The compounds are suitable for the treatment of lipid metabolism disorders which are beneficially influenced by stimulation of the hepatic LDL receptor.
Also described are the compounds of the formula IV ##STR1## and the salts thereof.

REFERENCES:
patent: 4285946 (1981-08-01), Kampe et al.
patent: 4705792 (1987-11-01), Granzer et al.
patent: 5571816 (1996-11-01), Kampe

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