Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1985-04-19
1987-11-17
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 68, 4351722, 43524027, 435810, 436501, 436531, 436547, 436548, 436800, 436808, 436809, 436 83, 530387, 935 89, 935 95, 935106, 935110, G01N 3353, G01N 33577, C12N 1500
Patent
active
047074434
ABSTRACT:
The present invention discloses a sandwich method and a kit for assaying interleukin-2 receptor (IL-2R) in a sample. The method comprises determining reactivity of said sample with a plurality of ligands, each said ligand having binding affinity for a specific site on the receptor, said site being different for each said ligand and distinct from interleukin-2 binding site on the receptor. The invention also discloses a method of detecting such disturbed or abnormal conditions in humans which release soluble IL-2R in the body fluid.
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patent: 4376110 (1983-08-01), David et al.
patent: 4411993 (1983-10-01), Gillis
patent: 4536479 (1985-08-01), Vander-Mallie
patent: 4545985 (1985-08-01), Pastan et al.
patent: 4578335 (1986-03-01), Urdal et al.
Kohler et al, Nature, vol. 256, pp. 495-497, 1975.
Depper et al, Journal of Immunology, vol. 131(2), pp. 690-696, 1983.
Biddison William
Greene Warner
Leonard Warren
Nelson David
Rubin Laurence
Nucker Christine M.
The United States of America as represented by the Secretary of
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