Soluble hydrophilic polymers and process for producing the same

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 28, 424 81, 424DIG13, A61K 3174, A61K 3178, A61K 970

Patent

active

039976602

ABSTRACT:
Soluble, hydrophilic polymers suitable for medical use and as blood plasma substitutes comprising low molecular weight polymer derived from at least one monomer of an acrylamide type material or a mono-ester of an acrylic type acid and a glycol which is condensed with bifunctional compounds to form a condensation polymer having increased molecular weight and enzymatically cleavable cross-links. The hydrophilic polymer is produced by polymerizing the acrylamide type material or mono-ester mentioned above to form a low molecular weight polymer which is then condensed with a bifunctional compound to form a high molecular weight condensation polymer having enzymatically cleavable cross-links.

REFERENCES:
patent: 3086887 (1963-04-01), Habib
patent: 3245941 (1966-04-01), Mayer
patent: 3415768 (1968-12-01), Dieterich
patent: 3575946 (1971-04-01), Chromecek

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