Soluble human prolactin receptors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 711, 4353201, 435325, 4352523, 43525411, 536 235, 536 231, 530350, C12N 1500

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active

060837535

ABSTRACT:
Soluble polypeptides of human prolactin receptor, corresponding to products expressed from differentially spliced mRNA and obtainable from various human tissues, are reported and recombinant molecules containing nucleic acid sequences encoding the soluble polypeptides of human prolactin receptor can be constructed and inserted into expression vectors for production in transformed host cells.

REFERENCES:
patent: 4992378 (1991-02-01), Kelly et al.
patent: 5605885 (1997-02-01), Bernton et al.
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P. E. Lobie et al., Prolactin Receptor Expression in the Gastrointestinal Tract: Characterization of the Prolactin Receptor of Gastric Mucosa, Journal of Endocrinology, 139, 371-382, 1993.
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Maria Rozakis-Adcock and Paul A. Kelly, Identification of Ligand Binding Determinants of the Prolactin Receptor, The Journal of Biological Chemistry, vol. 267, No. 11, 7428-7433, 1992.
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Margrit Urbanek et al., Functional Characterization of the Alternatively Spliced, Placental Human Growth Hormone Receptor, The Journal of Biological Chemistry, vol. 268, 19025-19032, Sep. 1993.

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