Soluble human prolactin receptors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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530350, 536 235, 536 231, C12N 1500

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active

060837144

ABSTRACT:
Soluble polypeptides of human prolactin receptor, corresponding to products expressed from differentially spliced mRNA and obtainable from various human tissues, are reported and recombinant molecules containing nucleic acid sequences encoding the soluble polypeptides of human prolactin receptor can be constructed and inserted into expression vectors for production in transformed host cells.

REFERENCES:
patent: 4992378 (1991-02-01), Kelly et al.
patent: 5605885 (1997-02-01), Bernton et al.
Jean-Marie Boutin et al., Cloning and Expression of the Rat Prolactin Receptor, a Member of the Growth Hormone/Prolactin Receptor Gene Family, Cell, vol. 53, 69-77, 1988.
Jean-Marie Boutin et al., Identification of a cDNA Encoding a Long Form of Prolactin Receptor in Human Hepatoma and Breat Cancer Cells, Molecular Endocrinology, vol. 3, No. 9, 1455-1461, 1989.
Brian C. Cunningham et al., Zinc Mediation of the Binding of Human Growth Hormone to the Human Prolactin Receptor, Science, vol. 250, 1709-1712, 1990.
Nazario Esposito et al., Expression of Two Isoforms of the Human Growth Hormone Receptor in Normal Liver and Hepatocarcinoma, Molecular and Celluar Endocrinology, 103, 13-20, 1994.
Germaine FUH and James A. Wells, Prolactin Receptor Antagonists That Inhibit the Growth of Breast Cancer Cell Lines, The Journal of Biological Chemistry, vol. 270, No. 22, 13133-13137, 1995.
Paul A. Kelly et al., The Growth Hormone/Prolactin Receptor Family, Recent Progress in Hormone Research, vol. 48, pp. 123-164, 1993.
Laurence Lesueur et al., Roles of Extracellular and Cytoplasmic Domains of the Prolactin Receptor in Signal Transduction to Milk Protein Genes, Molecular Endocrinology, vol. 7, No. 9, 1178-1184, 1993.
David W. Leung et al., Growth Hormone Receptor and Serum Binding Protein: Purification, Ctoning and Expression, Nature, vol. 330, 537-543, Dec. 1987.
P. E. Lobie et al., Prolactin Receptor Expression in the Gastrointestinal Tract: Characterization of the Prolactin Receptor of Gastric Mucosa, Journal of Endocrinology, 139, 371-382, 1993.
Isabelle Pellegrini et al., Expression of Prolactin and Its Receptor in Human Lymphoid Cells, Molecular Endocrinology, vol. 6, No. 7, 1023-1031, 1992.
Maria Rozakis-Adcock and Paul A. Kelly, Identification of Ligand Binding Determinants of the Prolactin Receptor, The Journal of Biological Chemistry, vol. 267, No. 11, 7428-7433, 1992.
Maria Rozakis-Adcock and Paul A. Kelly, Mutational Analysis of the Ligand-Binding Domain of the Prolactin Receptor, The Journal of Biological Chemistry, vol. 266, No. 25, 16472-16477, 1991.
Margrit Urbanek et al., Functional Characterization of the Alternatively Spliced, Placental Human Growth Hormone Receptor, The Journal of Biological Chemistry, vol. 268, 19025-19032, Sep. 1993.

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