Soluble, gum-containing, coated chewable tablet

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical

Reexamination Certificate

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Details

C424S465000, C424S484000, C424S439000

Reexamination Certificate

active

06932979

ABSTRACT:
The soluble, rubber-containing, coated chewable tablet contains chewable components, syrup components and fat or wax components and optionally fillers. It can be prepared by a process in which pulverulent chewable components are mixed with the molten fat or wax components. The mixture, with the addition of at least one syrup component, then becomes a crumbly material, which is then cooled to below 0° C., then milled to a particle size of not more than 5 mm and, after cooling to below 10° C., compressed to give tablets which are coated in a known manner. The finished product—due to compression of the cooled granules—presumably has a partially granular structure in which the moisture has been initially immobilized by the low temperature. After compression, this moisture becomes mobile as a result of heating (in particular during the coating process) and migrates or diffuses—initially at the surface—into the water-soluble ingredients present. These are partially dissolved and give a highly viscous, thixotropic, chewable material.

REFERENCES:
patent: 4753800 (1988-06-01), Mozda
patent: 5637313 (1997-06-01), Chau et al.
patent: 5648092 (1997-07-01), Weckenmann et al.
patent: 212641 (1987-03-01), None
patent: 1538280 (1979-01-01), None
patent: 8603967 (1986-07-01), None
The Merck Index (Merck & Co., Inc 1983) p. 4243.
International Search Report.
Derwent Publications Ltd.—XP 002049401 (Abstract).

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