Soluble fusion proteins comprising heterologous polypeptides

Details Soluble fusion proteins comprising heterologous polypeptides Soluble fusion proteins comprising heterologous polypeptides

2011-08-02

2011-08-02

Ulm, John D (Department: 1649)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S252300, C435S320100, C530S350000, C536S023400

Reexamination Certificate

active

07989183

ABSTRACT:
A soluble fusion protein is disclosed. The soluble fusion protein comprises at least one soluble polypeptide and a heterologous polypeptide being fused thereto, the heterologous polypeptide being normally insoluble and/or suboptimally expressed when expressed in a cell, wherein the at least one soluble polypeptide has an amino acid sequence at least 65 percent similar to SEQ ID NO: 1 and/or 2, as determined using the Standard protein-protein BLAST [blastp] software of the NCBI.

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