Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1993-10-25
1998-11-03
Cunningham, Thomas M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
4241851, 435 693, 530300, 530350, C07K 14705, A61K 3817
Patent
active
058310363
ABSTRACT:
The present invention relates to intercellular adhesion molecules (ICAM-1) which are involved in the process through which lymphocytes recognize and migrate to sites of inflammation as well as attach to cellular substrates during inflammation. The invention is directed toward such molecules, screening assays for identifying such molecules and antibodies capable of binding such molecules. The invention also includes uses for adhesion molecules and for the antibodies that are capable of binding them.
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Dustin Michael L.
Marlin Steven D.
Rothlein Robert
Springer Timothy A.
Cunningham Thomas M.
Dana Farber Cancer Institute
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