Soluble form of GMP-140

Details Soluble form of GMP-140 Soluble form of GMP-140

1994-07-08

1998-06-16

Walsh, Stephen

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 691, 435325, 4352523, 43525411, 530395, 536235, C07K 1400, C12N 1509

Patent

active

057672415

ABSTRACT:
The invention is directed to a purified soluble form of human granule membrane protein 140 (GMP-140) which lacks an amino acid sequence comprising a transmembrane domain and which is effective in inhibiting leukocyte adherence mediated by granule membrane protein 140. Nucleic acid encoding the soluble form of GMP-140 is disclosed.

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